연세대학교 의과대학 예방의학교실 환경역학연구실

논문(Publications)

HOME
논문(Publications)

Associations between short-term exposure to air pollution and thyroid function in a representative sample of the Korean population

작성자
관리자
작성일자
2024-08-02 10:48
조회수
159
Issue Date
2024-07
Type
Article

Authors: Kyoung-Nam Kim ; SoHyun Park ; Junseo Choi ; Il-Ung Hwang

Citation: ENVIRONMENTAL RESEARCH, Vol.252(Pt 4) : 119018, 2024-07

Journal Title: ENVIRONMENTAL RESEARCH

ISSN: 0013-9351

Issue Date: 2024-07

MeSH: Adult ; Aged ; Air Pollutants* / adverse effects ; Air Pollutants* / analysis ; Air Pollution* / adverse effects ; Air Pollution* / analysis ; Environmental Exposure* / adverse effects ; Female ; Humans ; Male ; Middle Aged ; Nutrition Surveys ; Particulate Matter / adverse effects ; Particulate Matter / analysis ; Republic of Korea ; Thyroid Gland* / drug effects ; Thyrotropin / blood ; Young Adult

Keywords: Air pollution ; General population ; Quantile g-computation ; Short-term effects ; Thyroid function

Abstract: Background: Disruption of thyroid function can profoundly affect various organ systems. However, studies on the association between air pollution and thyroid function are relatively scarce and most studies have focused on the long-term effects of air pollution among pregnant women. Objectives: This study aimed to explore the associations between short-term exposure to air pollution and thyroid function in the general population. Methods: Data from the Korea National Health and Nutrition Examination Survey (2013–2015) were analyzed (n = 5,626). Air pollution concentrations in residential addresses were estimated using Community Multiscale Air Quality models. The moving averages of air pollution over 7 days were set as exposure variables through exploratory analyses. Linear regression and quantile g-computation models were constructed to assess the effects of individual air pollutants and air pollution mixture, respectively. Results: A 10-ppb increase in NO2 (18.8-μg/m3 increase) and CO (11.5-μg/m3 increase) was associated with 2.43% [95% confidence interval (CI): 0.42, 4.48] and 0.19% (95% CI: 0.01, 0.36) higher thyroid-stimulating hormone (TSH) levels, respectively. A 10-μg/m3 increase in PM2.5 and a 10-ppb increase in O3 (19.6-μg/m3 increment) were associated with 0.87% (95% CI: 1.47, −0.27) and 0.59% (95% CI: 1.18, −0.001) lower free thyroxine (fT4) levels, respectively. A simultaneous quartile increase in PM2.5, NO2, O3, and CO levels was associated with lower fT4 but not TSH levels. Conclusions: As the subtle changes in thyroid function can affect various organ systems, the present results may have substantial public health implications despite the relatively modest effect sizes. Because this was a cross-sectional study, it is necessary to conduct further experimental or repeated-measures studies to consolidate the current results. © 2024 Elsevier Inc.

Full Text: https://www.sciencedirect.com/science/article/pii/S0013935124009228

DOI: 10.1016/j.envres.2024.119018

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers

Yonsei Authors: Kim, Kyoung-Nam(김경남)

URI: https://ir.ymlib.yonsei.ac.kr/handle/22282913/200019

사서에게 알리기

Estimation of Attributable Risk and Direct Medical and Non-Medical Costs of Major Mental Disorders Associated With Air Pollution Exposures Among Children and Adolescents in the Republic of Korea, 2011-2019

이전글이 없습니다.