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Estimation of Attributable Risk and Direct Medical and Non-Medical Costs of Major Mental Disorders Associated With Air Pollution Exposures Among Children and Adolescents in the Republic of Korea, 2011-2019

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2024-10-21 22:30
조회수
72
Issue Date
2024-08
Type
Article

Authors: Yae Won Ha ; Tae Hyun Kim ; Dae Ryong Kang ; Ki-Soo Park ; Dong Chun Shin ; Jaelim Cho ; Changsoo Kim

Citation: JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.39(30) : e218, 2024-08

Journal Title: JOURNAL OF KOREAN MEDICAL SCIENCE

ISSN: 1011-8934

Issue Date: 2024-08

MeSH: Adolescent ; Air Pollutants / adverse effects ; Air Pollutants / analysis ; Air Pollution* / adverse effects ; Attention Deficit Disorder with Hyperactivity* / epidemiology ; Attention Deficit Disorder with Hyperactivity* / etiology ; Autism Spectrum Disorder / epidemiology ; Autism Spectrum Disorder / etiology ; Child ; Child, Preschool ; Environmental Exposure / adverse effects ; Female ; Health Care Costs ; Humans ; Male ; Mental Disorders / epidemiology ; Mental Disorders / etiology ; Particulate Matter* / adverse effects ; Particulate Matter* / analysis ; Republic of Korea / epidemiology ; Risk Factors ; Sulfur Dioxide / adverse effects ; Sulfur Dioxide / analysis

Keywords: Adolescents ; Air Pollution ; Burden ; Children ; Mental Disorders ; PM10 ; PM2.5 ; SO2

Abstract: Background: Recent studies have reported the burden of attention deficit hyperactivity disorder [ADHD], autism spectrum disorder [ASD], and depressive disorder. Also, there is mounting evidence on the effects of environmental factors, such as ambient air pollution, on these disorders among children and adolescents. However, few studies have evaluated the burden of mental disorders attributable to air pollution exposure in children and adolescents.

Methods: We estimated the risk ratios of major mental disorders (ADHD, ASD, and depressive disorder) associated with air pollutants among children and adolescents using time-series data (2011–2019) obtained from a nationwide air pollution monitoring network and healthcare utilization claims data in the Republic of Korea. Based on the estimated risk ratios, we determined the population attributable fraction (PAF) and calculated the medical costs of major mental disorders attributable to air pollution.

Results: A total of 33,598 patients were diagnosed with major mental disorders during 9 years. The PAFs for all the major mental disorders were estimated at 6.9% (particulate matter < 10 μm [PM10]), 3.7% (PM2.5), and 2.2% (sulfur dioxide [SO2]). The PAF of PM10 was highest for depressive disorder (9.2%), followed by ASD (8.4%) and ADHD (5.2%). The direct medical costs of all major mental disorders attributable to PM10 and SO2 decreased during the study period.

Conclusion: This study assessed the burden of major mental disorders attributable to air pollution exposure in children and adolescents. We found that PM10, PM2.5, and SO2 attributed 7%, 4%, and 2% respectively, to the risk of major mental disorders among children and adolescents.

Files in This Item:: T202405428.pdf Download

DOI: 39106887

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers

Yonsei Authors: Kim, Chang Soo(김창수) https://orcid.org/0000-0002-5940-5649
Kim, Tae Hyun(김태현) https://orcid.org/0000-0003-1053-8958
Shin, Dong Chun(신동천) https://orcid.org/0000-0003-4252-2280
Cho, Jae Lim(조재림)

URI: https://ir.ymlib.yonsei.ac.kr/handle/22282913/200501

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